Liya Yin Selected Research

Carboxylesterase (Hydrolase S)

1/2021	Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice.
4/2020	Hepatocyte-Specific Expression of Human Carboxylesterase 1 Attenuates Diet-Induced Steatohepatitis and Hyperlipidemia in Mice.
12/2017	Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr -/- mice.
4/2016	Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4α and Protects Against Alcohol- and MCD diet-induced Liver Injury.
1/2016	Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice.

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Liya Yin Research Topics

Disease

9	Fatty Liver 11/2021 - 02/2011
8	Atherosclerosis 01/2021 - 01/2010
6	Inflammation (Inflammations) 11/2021 - 04/2016
6	Non-alcoholic Fatty Liver Disease 01/2021 - 06/2015
3	Ischemia 01/2022 - 08/2013
3	Obesity 01/2018 - 01/2016
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 05/2016
2	Insulin Resistance 01/2021 - 01/2014
2	Hyperlipidemias (Hyperlipidemia) 04/2020 - 12/2017
2	Myocardial Ischemia (Ischemic Heart Diseases) 01/2017 - 03/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 05/2016 - 04/2016
2	Alcoholic Fatty Liver 04/2016 - 06/2015
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Neoplasms (Cancer) 01/2021
1	Vascular Diseases (Vascular Disease) 10/2019
1	Hypercholesterolemia 01/2018
1	Cicatrix (Scar) 01/2017
1	Infarction (Infarctions) 01/2017
1	Myocardial Infarction 01/2017
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 04/2016
1	Inborn Genetic Diseases (Disease, Hereditary) 09/2011
1	Mason-Type Diabetes 02/2011
1	Progeria (Hutchinson Gilford Syndrome) 07/2009
1	Hyperinsulinism (Hyperinsulinemia) 12/2007
1	Hyperglycemia 12/2007

Drug/Important Bio-Agent (IBA)

7	CholesterolIBA 01/2021 - 02/2011
6	Triglycerides (Triacylglycerol)IBA 01/2021 - 02/2011
5	Hepatocyte Nuclear FactorsIBA 11/2021 - 02/2011
5	Carboxylesterase (Hydrolase S)IBA 01/2021 - 01/2016
4	Fatty Acids (Saturated Fatty Acids)IBA 11/2021 - 06/2019
4	LipidsIBA 01/2021 - 01/2010
3	FructoseIBA 01/2021 - 06/2019
3	Lipoproteins (Lipoprotein)IBA 01/2021 - 01/2010
3	Apolipoproteins E (ApoE)IBA 01/2021 - 06/2015
3	Bile Acids and Salts (Bile Acids)IBA 01/2021 - 10/2016
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 12/2007
2	Mitochondrial DNA (mtDNA)IBA 01/2022 - 05/2016
2	Sterol Regulatory Element Binding Protein 1IBA 01/2021 - 06/2019
2	Adenosine Triphosphate (ATP)IBA 01/2020 - 05/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2016 - 08/2013
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2022
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Activating Transcription Factor 3IBA 11/2021
1	GelatinasesIBA 01/2021
1	Nonesterified Fatty Acids (NEFA)IBA 01/2021
1	Dextrans (Dextran)FDA Link 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	cadherin 5IBA 01/2021
1	SterolsIBA 01/2021
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2020
1	Biological ProductsIBA 10/2019
1	MicroRNAs (MicroRNA)IBA 10/2019
1	Proteins (Proteins, Gene)FDA Link 10/2019
1	Lipocalin-2IBA 06/2019
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2019
1	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 01/2019
1	6-ethyl-24-norcholane-3,7,23-triol-23 sulfateIBA 01/2018
1	PolymersIBA 01/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	Free RadicalsIBA 05/2016
1	AcetaldehydeIBA 04/2016
1	Ethanol (Ethyl Alcohol)IBA 04/2016
1	Methionine (L-Methionine)FDA Link 04/2016
1	Choline (Choline Chloride)IBA 04/2016
1	Hepatocyte Nuclear Factor 4IBA 01/2016
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 06/2015
1	VLDL LipoproteinsIBA 06/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2013
1	RotenoneIBA 08/2013
1	salicylhydroxamic acid (SHAM)IBA 08/2013
1	LaminsIBA 09/2011
1	HDL CholesterolIBA 02/2011
1	lamin CIBA 07/2009
1	prelamin AIBA 07/2009
1	Antisense OligonucleotidesIBA 07/2009
1	RNA Splice SitesIBA 07/2009

Therapy/Procedure

2	Therapeutics 01/2017 - 03/2015
1	Operative Surgical Procedures 01/2017
1	Ligation 01/2017